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Predominant V(H) genes expressed in innate antibodies are associated with distinctive antigen-binding sites

Antibodies to phosphatidylcholine (PtC), a common constituent of mammalian and bacterial cell membranes, represent a large proportion of the natural antibody repertoire in mice. Previous studies of several mouse strains (e.g., C57BL/6) have shown that anti-PtC antibodies are mainly encoded by the V(...

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Autori principali: Seidl, Katherine J., Wilshire, Jennifer A., MacKenzie, John D., Kantor, Aaron B., Herzenberg, Leonard A., Herzenberg, Leonore A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC26771/
https://ncbi.nlm.nih.gov/pubmed/10051629
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