Chronic elevation of plasma thioredoxin: Inhibition of chemotaxis and curtailment of life expectancy in AIDS

Thioredoxin (Trx) is an intracellular redox protein with extracellular cytokine-like and chemokine-like activities. We show here that, although plasma Trx levels are unrelated to survival of HIV-infected individuals with CD4 cell counts above 200/μl blood, survival is significantly impaired (P = 0.0...

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Autores principales: Nakamura, Hajime, De Rosa, Stephen C., Yodoi, Junji, Holmgren, Arne, Ghezzi, Pietro, Herzenberg, Leonard A., Herzenberg, Leonore A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2001
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC30199/
https://ncbi.nlm.nih.gov/pubmed/11226300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.041624998
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