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Circulating thioredoxin suppresses lipopolysaccharide-induced neutrophil chemotaxis

Thioredoxin (Trx), a redox enzyme with a conserved active site (Cys-32–Gly–Pro–Cys-35), is induced and secreted into circulation in response to inflammation. Studies here demonstrate that elevating Trx levels in circulation either by i.v. injection of recombinant Trx or stimulating Trx release in Tr...

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Detalhes bibliográficos
Main Authors: Nakamura, Hajime, Herzenberg, Leonore A., Bai, Jie, Araya, Shinichi, Kondo, Norihiko, Nishinaka, Yumiko, Herzenberg, Leonard A., Yodoi, Junji
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC64997/
https://ncbi.nlm.nih.gov/pubmed/11742067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191498798
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