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Circulating thioredoxin suppresses lipopolysaccharide-induced neutrophil chemotaxis

Thioredoxin (Trx), a redox enzyme with a conserved active site (Cys-32–Gly–Pro–Cys-35), is induced and secreted into circulation in response to inflammation. Studies here demonstrate that elevating Trx levels in circulation either by i.v. injection of recombinant Trx or stimulating Trx release in Tr...

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Autori principali: Nakamura, Hajime, Herzenberg, Leonore A., Bai, Jie, Araya, Shinichi, Kondo, Norihiko, Nishinaka, Yumiko, Herzenberg, Leonard A., Yodoi, Junji
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC64997/
https://ncbi.nlm.nih.gov/pubmed/11742067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191498798
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