Circulating thioredoxin suppresses lipopolysaccharide-induced neutrophil chemotaxis

Thioredoxin (Trx), a redox enzyme with a conserved active site (Cys-32–Gly–Pro–Cys-35), is induced and secreted into circulation in response to inflammation. Studies here demonstrate that elevating Trx levels in circulation either by i.v. injection of recombinant Trx or stimulating Trx release in Tr...

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Bibliografiske detaljer
Main Authors: Nakamura, Hajime, Herzenberg, Leonore A., Bai, Jie, Araya, Shinichi, Kondo, Norihiko, Nishinaka, Yumiko, Herzenberg, Leonard A., Yodoi, Junji
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC64997/
https://ncbi.nlm.nih.gov/pubmed/11742067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191498798
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