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Enzymatic reduction of alloxan by thioredoxin and NADPH-thioredoxin reductase.

Alloxan reacts with certain sulfhydryl groups either by chemical modification or reduction to dialuric acid. The effects of the drug on NADPH-thioredoxin oxidoreductase, EC 1.6.4.5] and thioredoxin-(SH)2, a ubiquitous thiol-dependent disulfide reductase system, are described. Alloxan was a direct su...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Holmgren, A, Lyckeborg, C
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1980
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933551/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.9.5149
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