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Enzymatic reduction of alloxan by thioredoxin and NADPH-thioredoxin reductase.

Alloxan reacts with certain sulfhydryl groups either by chemical modification or reduction to dialuric acid. The effects of the drug on NADPH-thioredoxin oxidoreductase, EC 1.6.4.5] and thioredoxin-(SH)2, a ubiquitous thiol-dependent disulfide reductase system, are described. Alloxan was a direct su...

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Detalhes bibliográficos
Main Authors: Holmgren, A, Lyckeborg, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC350014/
https://ncbi.nlm.nih.gov/pubmed/6933551
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