Glutathionylation of human thioredoxin: A possible crosstalk between the glutathione and thioredoxin systems

To identify proteins undergoing glutathionylation (formation of protein-glutathione mixed disulfides) in human T cell blasts, we radiolabeled the glutathione pool with (35)S, exposed cells to the oxidant diamide, and analyzed cellular proteins by two-dimensional electrophoresis. One of the proteins...

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Autori principali: Casagrande, Simona, Bonetto, Valentina, Fratelli, Maddalena, Gianazza, Elisabetta, Eberini, Ivano, Massignan, Tania, Salmona, Mario, Chang, Geng, Holmgren, Arne, Ghezzi, Pietro
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC125000/
https://ncbi.nlm.nih.gov/pubmed/12119401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152168599
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