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Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage

T cells bearing the class II-restricted, DO-T cell receptor (TCR) are CD4+ if their thymocyte precursors are positively selected on the class II protein, IAd, but they are almost all CD4- after positive selection on a class II for which they have higher avidity, IAb. DO-TCR+ T cells mature in H-2b m...

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Bibliografiske detaljer
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192895/
https://ncbi.nlm.nih.gov/pubmed/8920852
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