A bone marrow-derived stroma cell line, ST2, can support the differentiation of fetal thymocytes from the CD4(−)CD8(−)double negative to the CD4(+)CD8(+) double positive differentiation stage in vitro

T-cell precursors differentiate into mature T cells predominantly in the thymus. However, it has also been reported that T-cell precursors mature in extrathymic organs such as the liver, bone marrow, or intestines. In order to investigate the nature of the extrathymic microenvironment that supports...

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Autori principali: Tong, J-J, Kishi, H, Matsuda, T, Muraguchi, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1999
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326888/
https://ncbi.nlm.nih.gov/pubmed/10457222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00822.x
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