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Modulation of promiscuous T cell receptor recognition by mutagenesis of CDR2 residues

The T cell receptor (TCR) recognizes a ligand composed of a major histocompatibility complex (MHC) molecule and a peptide antigen. Prior studies of murine T cell clones have demonstrated that residues in the CDR3 region of TCR interact with amino acids in the peptide during MHC- restricted antigen r...

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Detalhes bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192576/
https://ncbi.nlm.nih.gov/pubmed/8642315
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