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Modulation of promiscuous T cell receptor recognition by mutagenesis of CDR2 residues
The T cell receptor (TCR) recognizes a ligand composed of a major histocompatibility complex (MHC) molecule and a peptide antigen. Prior studies of murine T cell clones have demonstrated that residues in the CDR3 region of TCR interact with amino acids in the peptide during MHC- restricted antigen r...
Gespeichert in:
| Format: | Artigo |
|---|---|
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
1996
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2192576/ https://ncbi.nlm.nih.gov/pubmed/8642315 |
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