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Maturational arrest from CD4+8+ to CD4+8- thymocytes in a mutant strain (LEC) of rat

A mutant strain (LEC) of rats was found to have a novel defect in T cell maturation, that is, arrest of differentiation from CD4+8+ to CD4+8- but not to CD4-8+ thymocytes. FACS analyses demonstrated a deficiency in the CD4+8- T cell subset in the thymus and a marked decrease in CD4+ T cells in perip...

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Библиографические подробности
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 1990
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188753/
https://ncbi.nlm.nih.gov/pubmed/2147947
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