Unresponsiveness of CD4-8+/- thymocytes to lectin stimulation in LEC mutant rats.

A mutant strain of rat, LEC, shows a novel arrest of T-cell maturation from CD4+8+ to CD4+8-, but not to CD4-8+ cells in the thymus. The responsible mutant locus is designated the thid, which was acted upon in a recessive manner of inheritance. We found that LEC rat thymocytes failed to respond to i...

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Autors principals: Sakai, T, Agui, T, Wei, K, Oka, M, Hisaeda, H, Nagasawa, H, Himeno, K, Matsumoto, K, Kaichun, W
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364308/
https://ncbi.nlm.nih.gov/pubmed/9824479
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