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Differentiation of thymocytes from CD3-CD4-CD8- through CD3-CD4-CD8+ into more mature stages induced by a thymic stromal cell clone.

We have investigated the capacity of our established thymic stromal cell clone (MRL104.8a) or its derived factor(s) to induce the differentiation of immature thymocytes. Culture of purified adult murine double-negative (CD4-CD8-, indicated here as CD4-8-) thymocytes on the MRL104.8a thymic stromal c...

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Detalhes bibliográficos
Main Authors: Tatsumi, Y, Kumanogoh, A, Saitoh, M, Mizushima, Y, Kimura, K, Suzuki, S, Yagi, H, Horiuchi, A, Ogata, M, Hamaoka, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC53768/
https://ncbi.nlm.nih.gov/pubmed/2138784
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