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Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck

Antibody-mediated CD4 crosslinking results in increased tyrosine phosphorylation and tyrosine kinase activity of the associated p56lck. Treatment with anti-CD4 and anti-Ig also induced the phosphorylation of p56lck in a CD45- mutant cell line, indicating that the increase in phosphotyrosine content...

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Detalhes bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188152/
https://ncbi.nlm.nih.gov/pubmed/2141630
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