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How the Discovery of the CD4/CD8-p56(lck) Complexes Changed Immunology and Immunotherapy

The past 25 years have seen enormous progress in uncovering the receptors and signaling mechanisms on T-cells that activate their various effecter functions. Until the late 1980s, most studies on T-cells had focused on the influx of calcium and the levels of cAMP/GMP in T-cells. My laboratory then u...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Autor principal: Rudd, Christopher E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005572/
https://ncbi.nlm.nih.gov/pubmed/33791292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.626095
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