The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.

Many mammalian receptors have been found to regulate cell growth by virtue of a protein-tyrosine kinase domain in their cytoplasmic tail. We recently described an association of the CD4 antigen with a T-cell-specific protein-tyrosine kinase (p56lck; formerly termed pp58lck; EC 2.7.1.112). This inter...

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Bibliographische Detailangaben
Hauptverfasser: Barber, E K, Dasgupta, J D, Schlossman, S F, Trevillyan, J M, Rudd, C E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC287114/
https://ncbi.nlm.nih.gov/pubmed/2470098
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