Llwytho...
Nucleation-dependent conformational conversion of the Y145Stop variant of human prion protein: Structural clues for prion propagation
One of the most intriguing disease-related mutations in human prion protein (PrP) is the Tyr to Stop codon substitution at position 145. This mutation results in a Gerstmann–Straussler–Scheinker-like disease with extensive PrP amyloid deposits in the brain. Here, we provide evidence for a spontaneou...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
National Academy of Sciences
2003
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC218714/ https://ncbi.nlm.nih.gov/pubmed/14519851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2033281100 |
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