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Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

The synthesis of fatty acids and cholesterol, the building blocks of membranes, is regulated by three membrane-bound transcription factors: sterol regulatory element-binding proteins (SREBP)-1a, -1c, and -2. Their function in liver has been characterized in transgenic mice that overexpress each SREB...

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Detalhes bibliográficos
Main Authors: Horton, Jay D., Shah, Nila A., Warrington, Janet A., Anderson, Norma N., Park, Sahng Wook, Brown, Michael S., Goldstein, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC218707/
https://ncbi.nlm.nih.gov/pubmed/14512514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1534923100
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