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The spindle checkpoint requires cyclin-dependent kinase activity
The spindle checkpoint prevents anaphase onset until completion of mitotic spindle assembly by restraining activation of the ubiquitin ligase anaphase-promoting complex/cyclosome–Cdc20 (APC/C(Cdc20)). We show that the spindle checkpoint requires mitotic cyclin-dependent kinase (cdk) activity. Inhibi...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC218146/ https://ncbi.nlm.nih.gov/pubmed/14561775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.267603 |
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