The spindle checkpoint requires cyclin-dependent kinase activity

The spindle checkpoint prevents anaphase onset until completion of mitotic spindle assembly by restraining activation of the ubiquitin ligase anaphase-promoting complex/cyclosome–Cdc20 (APC/C(Cdc20)). We show that the spindle checkpoint requires mitotic cyclin-dependent kinase (cdk) activity. Inhibi...

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Bibliografske podrobnosti
Main Authors: D'Angiolella, Vincenzo, Mari, Cecilia, Nocera, Donatella, Rametti, Linda, Grieco, Domenico
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2003
Teme:
Research Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC218146/
https://ncbi.nlm.nih.gov/pubmed/14561775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.267603
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