Novel Functional Assay for Spindle-Assembly Checkpoint by Cyclin-Dependent Kinase Activity to Predict Taxane Chemosensitivity in Breast Tumor Patient

Taxanes are among the drugs most commonly used for preoperative chemotherapy for breast cancer. Taxanes induce mitotic arrest and subsequent apoptosis. The spindle-assembly checkpoint (SAC) is known to be activated during mitosis, along with cyclin-dependent kinase-1 (CDK1), and is required for taxa...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Torikoshi, Yasuhiro, Gohda, Keigo, Davis, Michelle L., Symmans, W. Fraser, Pusztai, Lajos, Kazansky, Anna, Nakayama, Satoshi, Yoshida, Tomokazu, Matsushima, Tomoko, Hortobagyi, Gabriel N., Ishihara, Hideki, Kim, Seung Jin, Noguchi, Shinzaburo, Ueno, Naoto T.
פורמט: Artigo
שפה:Inglês
יצא לאור: Ivyspring International Publisher 2013
נושאים:
Short Research Communication
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842438/
https://ncbi.nlm.nih.gov/pubmed/24312139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.6248
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים