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Prediction of paclitaxel sensitivity by CDK1 and CDK2 activity in human breast cancer cells

INTRODUCTION: Paclitaxel is used widely in the treatment of breast cancer. Not all tumors respond to this drug, however, and the characteristics that distinguish resistant tumors from sensitive tumors are not well defined. Activation of the spindle assembly checkpoint is required for paclitaxel-indu...

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書誌詳細
主要な著者: Nakayama, Satoshi, Torikoshi, Yasuhiro, Takahashi, Takeshi, Yoshida, Tomokazu, Sudo, Tamotsu, Matsushima, Tomoko, Kawasaki, Yuko, Katayama, Aya, Gohda, Keigo, Hortobagyi, Gabriel N, Noguchi, Shinzaburo, Sakai, Toshiyuki, Ishihara, Hideki, Ueno, Naoto T
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687717/
https://ncbi.nlm.nih.gov/pubmed/19239702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2231
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