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Prediction of paclitaxel sensitivity by CDK1 and CDK2 activity in human breast cancer cells
INTRODUCTION: Paclitaxel is used widely in the treatment of breast cancer. Not all tumors respond to this drug, however, and the characteristics that distinguish resistant tumors from sensitive tumors are not well defined. Activation of the spindle assembly checkpoint is required for paclitaxel-indu...
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| 主要な著者: | , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2687717/ https://ncbi.nlm.nih.gov/pubmed/19239702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2231 |
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