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A cyclin without CDKs: Cyclin F controls genome stability through ubiquitin-mediated proteolysis
Cell cycle transitions are driven by the periodic oscillations of cyclins, which bind and activate CDKs (cyclin-dependent kinases) to phosphorylate target substrates. Cyclin F uses a substrate recruitment strategy similar to that of the other cyclins, but its associated catalytic activity is substan...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597434/ https://ncbi.nlm.nih.gov/pubmed/23182110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2012.10.011 |
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