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A cyclin without CDKs: Cyclin F controls genome stability through ubiquitin-mediated proteolysis

Cell cycle transitions are driven by the periodic oscillations of cyclins, which bind and activate CDKs (cyclin-dependent kinases) to phosphorylate target substrates. Cyclin F uses a substrate recruitment strategy similar to that of the other cyclins, but its associated catalytic activity is substan...

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Detalhes bibliográficos
Main Authors: D'Angiolella, Vincenzo, Esencay, Mine, Pagano, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597434/
https://ncbi.nlm.nih.gov/pubmed/23182110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2012.10.011
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