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SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity via CP110 degradation
Generally, F-box proteins are the substrate recognition subunits of SCF (Skp1-Cul1-F-box protein) ubiquitin ligase complexes, which mediate the timely proteolysis of important eukaryotic regulatory proteins1,2. Mammalian genomes encode roughly 70 F-box proteins, but only a handful have established f...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946399/ https://ncbi.nlm.nih.gov/pubmed/20596027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09140 |
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