Genetic and Pharmacologic Evidence Links Oxidative Stress to Ventilator-induced Lung Injury in Mice

Rationale: Mechanical ventilation (MV) is an indispensable therapy for critically ill patients with acute lung injury and the adult respiratory distress syndrome. However, the mechanisms by which conventional MV induces lung injury remain unclear. Objectives: We hypothesized that disruption of the g...

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Detalhes bibliográficos
Main Authors: Papaiahgari, Srinivas, Yerrapureddy, Adi, Reddy, Swetha R., Reddy, Narsa M., Dodd-O, Jeffery M., Crow, Michael T., Grigoryev, Dimitry N., Barnes, Kathleen, Tuder, Rubin M., Yamamoto, Masayuki, Kensler, Thomas W., Biswal, Shyam, Mitzner, Wayne, Hassoun, Paul M., Reddy, Sekhar P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
Assuntos:
C. Critical Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176106/
https://ncbi.nlm.nih.gov/pubmed/17901416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200701-060OC
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