EGFR-Activated Signaling and Actin Remodeling Regulate Cyclic Stretch–Induced NRF2-ARE Activation

Cyclic stretch (CS) associated with mechanical ventilation (MV) can cause excessive alveolar and endothelial distention, resulting in lung injury and inflammation. Antioxidant enzymes (AOEs) play a major role in suppressing these effects. The transcription factor Nrf2, via the antioxidant response e...

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Bibliografske podrobnosti
Main Authors: Papaiahgari, Srinivas, Yerrapureddy, Adinarayana, Hassoun, Paul M., Garcia, Joe G. N., Birukov, Konstantin G., Reddy, Sekhar P.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2007
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899320/
https://ncbi.nlm.nih.gov/pubmed/17008637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0131OC
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