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Magnitude-dependent effects of cyclic stretch on HGF- and VEGF-induced pulmonary endothelial remodeling and barrier regulation

Mechanical ventilation at high tidal volumes compromises the blood-gas barrier and increases lung vascular permeability, which may lead to ventilator-induced lung injury and pulmonary edema. Using pulmonary endothelial cell (ECs) exposed to physiologically [5% cyclic stretch (CS)] and pathologically...

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Detalhes bibliográficos
Main Authors: Birukova, Anna A., Moldobaeva, Nurgul, Xing, Junjie, Birukov, Konstantin G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575947/
https://ncbi.nlm.nih.gov/pubmed/18689603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90236.2008
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