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Activation of Vascular Endothelial Growth Factor (VEGF) Receptor 2 Mediates Endothelial Permeability Caused by Cyclic Stretch

High tidal volume mechanical ventilation and the resultant excessive mechanical forces experienced by lung vascular endothelium are known to lead to increased vascular endothelial leak, but the underlying molecular mechanisms remain incompletely understood. One reported mechanotransduction pathway o...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tian, Yufeng, Gawlak, Grzegorz, O'Donnell, James J., Birukova, Anna A., Birukov, Konstantin G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858957/
https://ncbi.nlm.nih.gov/pubmed/26884340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.690487
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