Cytoplasmic Localization and the Choice of Ligand Determine Aggregate Formation by Androgen Receptor with Amplified Polyglutamine Stretch

Polyglutamine tract expansion in androgen receptor is a recognized cause of spinal and bulbar muscular atrophy (SBMA), an X-linked motor neuronopathy. Similar mutations have been identified in proteins associated with other neurodegenerative diseases. Recent studies have shown that amplified polyglu...

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Bibliographic Details
Main Authors: Becker, Matthias, Martin, Elke, Schneikert, Jean, Krug, Harald F., Cato, Andrew C.B.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2000
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175165/
https://ncbi.nlm.nih.gov/pubmed/10769019
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