Ładuje się......
Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation
CNS neurons are endowed with the ability to recover from cytotoxic insults associated with the accumulation of proteinaceous aggregates in mouse models of polyglutamine disease, but the cellular mechanism underlying this phenomenon is unknown. Here, we show that autophagy is essential for the elimin...
Zapisane w:
| Główni autorzy: | , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2005
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201602/ https://ncbi.nlm.nih.gov/pubmed/16141322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505801102 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|