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IL-2 and IL-15 Each Mediate De Novo Induction of FOXP3 Expression in Human Tumor Antigen-specific CD8 T Cells
Although FOXP3 is primarily expressed by regulatory CD4 T cells (T(reg)) in vivo, polyclonal activation of human CD8 T cells can result in the expression of FOXP3 in a fraction of CD8 T cells. However, the cellular lineage and mechanism of FOXP3 induction in CD8 T cells remain unclear. Here, we demo...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2174606/ https://ncbi.nlm.nih.gov/pubmed/17414320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3180336787 |
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