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Modulation by IL-2 of CD70 and CD27 Expression on CD8(+) T Cells: Importance for the Therapeutic Effectiveness of Cell Transfer Immunotherapy

Proper T cell function relies on the integration of signals delivered by Ag, cytokine, and costimulatory receptors. In this study, the interactions between IL-2, CD27, and its ligand CD70 and their effects on human T cell function were examined. Unstimulated CD8(+)T cells expressed relatively low le...

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Autors principals: Huang, Jianping, Kerstann, Keith W., Ahmadzadeh, Mojgan, Li, Yong F., El-Gamil, Mona, Rosenberg, Steven A., Robbins, Paul F.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1532931/
https://ncbi.nlm.nih.gov/pubmed/16751420
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