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Transition of late-stage effector T cells to CD27(+) CD28(+) tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy

In humans, the pathways of memory T-cell differentiation remain poorly defined. Recently, adoptive cell transfer (ACT) of tumor-reactive T lymphocytes to metastatic melanoma patients after nonmyeloablative chemotherapy has resulted in persistence of functional, tumor-reactive lymphocytes, regression...

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Main Authors: Powell, Daniel J., Dudley, Mark E., Robbins, Paul F., Rosenberg, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado: 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553211/
https://ncbi.nlm.nih.gov/pubmed/15345595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-06-2482
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