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IL-2 administration increases CD4(+)CD25(hi) Foxp3(+) regulatory T cells in cancer patients

Interleukin-2 (IL-2) is historically known as a T-cell growth factor. Accumulating evidence from knockout mice suggests that IL-2 is crucial for the homeostasis and function of CD4(+)CD25(+) regulatory T cells in vivo. However, the impact of administered IL-2 in an immune intact host has not been st...

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Detalhes bibliográficos
Main Authors: Ahmadzadeh, Mojgan, Rosenberg, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1473973/
https://ncbi.nlm.nih.gov/pubmed/16304057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2399
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