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TGF-β1 Attenuates the Acquisition and Expression of Effector Function by Tumor Antigen-Specific Human Memory CD8 T Cells

TGF-β1 is a potent immunoregulatory cytokine. However, its impact on the generation and effector function of Ag-specific human effector memory CD8 T cells had not been evaluated. Using Ag-specific CD8 T cells derived from melanoma patients immunized with the gp100 melanoma Ag, we demonstrate that th...

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Bibliografski detalji
Glavni autori: Ahmadzadeh, Mojgan, Rosenberg, Steven A.
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562293/
https://ncbi.nlm.nih.gov/pubmed/15843517
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