Oncogenic Ras Downregulates Rac Activity, Which Leads to Increased Rho Activity and Epithelial–Mesenchymal Transition

Proteins of the Rho family regulate cytoskeletal rearrangements in response to receptor stimulation and are involved in the establishment and maintenance of epithelial cell morphology. We recently showed that Rac is able to downregulate Rho activity and that the reciprocal balance between Rac and Rh...

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Hlavní autoři: Zondag, Gerben C.M., Evers, Eva E., ten Klooster, Jean P., Janssen, Lennert, van der Kammen, Rob A., Collard, John G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2000
Témata:
Brief Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174558/
https://ncbi.nlm.nih.gov/pubmed/10811819
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