Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation.

Although substantial evidence supports a critical role for the activation of Raf-1 and mitogen-activated protein kinases (MAPKs) in oncogenic Ras-mediated transformation, recent evidence suggests that Ras may activate a second signaling pathway which involves the Ras-related proteins Rac1 and RhoA....

Full description

Saved in:
Bibliographic Details
Main Authors: Khosravi-Far, R, Solski, P A, Clark, G J, Kinch, M S, Der, C J
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC230895/
https://ncbi.nlm.nih.gov/pubmed/7565796
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items