Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation.

Although substantial evidence supports a critical role for the activation of Raf-1 and mitogen-activated protein kinases (MAPKs) in oncogenic Ras-mediated transformation, recent evidence suggests that Ras may activate a second signaling pathway which involves the Ras-related proteins Rac1 and RhoA....

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Pubblicato in:	Mol Cell Biol
Autori principali:	Khosravi-Far, R, Solski, P A, Clark, G J, Kinch, M S, Der, C J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565796/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.11.6443
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