Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation.
Although substantial evidence supports a critical role for the activation of Raf-1 and mitogen-activated protein kinases (MAPKs) in oncogenic Ras-mediated transformation, recent evidence suggests that Ras may activate a second signaling pathway which involves the Ras-related proteins Rac1 and RhoA....
Guardat en:
| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1995
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565796/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.11.6443 |
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