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HDAC inhibitor valproic acid upregulates CAR in vitro and in vivo
BACKGROUND: The presence of CAR in diverse tumor types is heterogeneous with implications in tumor transduction efficiency in the context of adenoviral mediated cancer gene therapy. Preliminary studies suggest that CAR transcriptional regulation is modulated through histone acetylation and not throu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2174455/ https://ncbi.nlm.nih.gov/pubmed/17892546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-5-10 |
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