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Synergistic Antitumor Effects of Novel HDAC Inhibitors and Paclitaxel In Vitro and In Vivo

Preclinical studies support the therapeutic potential of histone deacetylases inhibitors (HDACi) in combination with taxanes. The efficacy of combination has been mainly ascribed to a cooperative effect on microtubule stabilization following tubulin acetylation. In the present study we investigated...

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מידע ביבליוגרפי
Main Authors: Zuco, Valentina, De Cesare, Michelandrea, Cincinelli, Raffaella, Nannei, Raffaella, Pisano, Claudio, Zaffaroni, Nadia, Zunino, Franco
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241602/
https://ncbi.nlm.nih.gov/pubmed/22194993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029085
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