Synergistic Antitumor Effects of Novel HDAC Inhibitors and Paclitaxel In Vitro and In Vivo

Preclinical studies support the therapeutic potential of histone deacetylases inhibitors (HDACi) in combination with taxanes. The efficacy of combination has been mainly ascribed to a cooperative effect on microtubule stabilization following tubulin acetylation. In the present study we investigated...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zuco, Valentina, De Cesare, Michelandrea, Cincinelli, Raffaella, Nannei, Raffaella, Pisano, Claudio, Zaffaroni, Nadia, Zunino, Franco
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2011
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241602/
https://ncbi.nlm.nih.gov/pubmed/22194993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029085
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