Synthesis and Evaluation of the Tumor Cell Growth Inhibitory Potential of New Putative HSP90 Inhibitors

Background: Heat shock protein 90 (HSP90) is a well-known target for cancer therapy. In a previous work, some of us have reported a series of 3-aryl-naphtho[2,3-d]isoxazole-4,9-diones as inhibitors of HSP90. Methods: In the present work, various compounds with new chromenopyridinone and thiochromeno...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ana Bizarro, Diana Sousa, Raquel T. Lima, Loana Musso, Raffaella Cincinelli, Vantina Zuco, Michelandrea De Cesare, Sabrina Dallavalle, M. Helena Vasconcelos
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2018-02-01
Colecção:Molecules
Assuntos:
HSP90
naphthoquinones
(thio)chromenopyridinones
antitumor
cell proliferation
cell cycle
apoptosis
tumor xenographs
Acesso em linha:http://www.mdpi.com/1420-3049/23/2/407
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados