Synergistic Antitumor Effects of Novel HDAC Inhibitors and Paclitaxel In Vitro and In Vivo

Preclinical studies support the therapeutic potential of histone deacetylases inhibitors (HDACi) in combination with taxanes. The efficacy of combination has been mainly ascribed to a cooperative effect on microtubule stabilization following tubulin acetylation. In the present study we investigated...

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Bibliografiske detaljer
Main Authors: Zuco, Valentina, De Cesare, Michelandrea, Cincinelli, Raffaella, Nannei, Raffaella, Pisano, Claudio, Zaffaroni, Nadia, Zunino, Franco
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241602/
https://ncbi.nlm.nih.gov/pubmed/22194993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029085
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