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G protein–coupled receptor/arrestin3 modulation of the endocytic machinery
Nonvisual arrestins (arr) modulate G protein–coupled receptor (GPCR) desensitization and internalization and bind to both clathrin (CL) and AP-2 components of the endocytic coated pit (CP). This raises the possibility that endocytosis of some GPCRs may be a consequence of arr-induced de novo CP form...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2174075/ https://ncbi.nlm.nih.gov/pubmed/11839771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200110132 |
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