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G protein–coupled receptor/arrestin3 modulation of the endocytic machinery

Nonvisual arrestins (arr) modulate G protein–coupled receptor (GPCR) desensitization and internalization and bind to both clathrin (CL) and AP-2 components of the endocytic coated pit (CP). This raises the possibility that endocytosis of some GPCRs may be a consequence of arr-induced de novo CP form...

詳細記述

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書誌詳細
主要な著者: Santini, Francesca, Gaidarov, Ibragim, Keen, James H.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174075/
https://ncbi.nlm.nih.gov/pubmed/11839771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200110132
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