CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo

BACKGROUND: Bacterial DNA containing motifs of unmethylated CpG dinucleotides (CpG-ODN) initiate an innate immune response mediated by the pattern recognition receptor Toll-like receptor 9 (TLR9). This leads in particular to the expression of proinflammatory mediators such as tumor necrosis factor (...

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Main Authors: Knuefermann, Pascal, Baumgarten, Georg, Koch, Alexander, Schwederski, Markus, Velten, Markus, Ehrentraut, Heidi, Mersmann, Jan, Meyer, Rainer, Hoeft, Andreas, Zacharowski, Kai, Grohé, Christian
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173891/
https://ncbi.nlm.nih.gov/pubmed/17925007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-8-72
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