Pre-conditioning with synthetic CpG-oligonucleotides attenuates myocardial ischemia/reperfusion injury via IL-10 up-regulation

The aim of the study was to investigate whether pre-conditioning with CpG-oligodeoxynucleotides (CpG-ODN) may change cardiac ischemia/reperfusion (I/R)-dependent inflammation and modulates infarct size and cardiac performance. WT and TLR9-deficient mice were pre-treated with 1668-, 1612- and H154-th...

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Detalhes bibliográficos
Main Authors: Markowski, P., Boehm, O., Goelz, L., Haesner, A. L., Ehrentraut, H., Bauerfeld, K., Tran, N., Zacharowski, K., Weisheit, C., Langhoff, P., Schwederski, M., Hilbert, T., Klaschik, S., Hoeft, A., Baumgarten, G., Meyer, R., Knuefermann, P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2013
Assuntos:
Original Contribution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778842/
https://ncbi.nlm.nih.gov/pubmed/23929312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-013-0376-7
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