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CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo
BACKGROUND: Bacterial DNA containing motifs of unmethylated CpG dinucleotides (CpG-ODN) initiate an innate immune response mediated by the pattern recognition receptor Toll-like receptor 9 (TLR9). This leads in particular to the expression of proinflammatory mediators such as tumor necrosis factor (...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173891/ https://ncbi.nlm.nih.gov/pubmed/17925007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-8-72 |
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