Systemically Administered Ligands of Toll-Like Receptor 2, -4, and -9 Induce Distinct Inflammatory Responses in the Murine Lung

Objective. To determine whether systemically administered TLR ligands differentially modulate pulmonary inflammation. Methods. Equipotent doses of LPS (20 mg/kg), CpG-ODN (1668-thioat 1 nmol/g), or LTA (15 mg/kg) were determined via TNF activity assay. C57BL/6 mice were challenged intraperitoneally....

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Detalhes bibliográficos
Main Authors: Ehrentraut, H., Meyer, R., Schwederski, M., Ehrentraut, S., Velten, M., Grohé, C., Knuefermann, P., Baumgarten, G., Boehm, O.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086362/
https://ncbi.nlm.nih.gov/pubmed/21547259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/746532
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