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TLR2 stimulation induces cardiac inflammation but not cardiac depression in vivo

BACKGROUND: Bacteria such as Staphylococcus aureus induce myocardial dysfunction in vivo. To rectify conflicting evidence about the role of TLR2 signaling and cardiac dysfunction, we hypothesized that the specific TLR2 agonist purified lipoteichoic acid (LTA) from S. aureus contributes to cardiac dy...

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Detalhes bibliográficos
Main Authors: Boehm, Olaf, Knuefermann, Pascal, Plueck, Johannes, Schwederski, Markus, Ehrentraut, Heidi, Kebir, Sied, Lohner, Ralph, Velten, Markus, Morath, Siegfried, Koch, Alexander, Zacharowski, Kai, Grohé, Christian, Hoeft, Andreas, Baumgarten, Georg, Meyer, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177531/
https://ncbi.nlm.nih.gov/pubmed/24171786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-10-33
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